Journal Watch

I hope you find that this Journal Watch is useful and will direct your journal reading when there are many to choose from and we all seem to be becoming more stretched for time.

SPANZA thanks all contributing writers from each centre and Catherine Olweny for taking on the role of ‘executive editor’ in 2011 to get the project up and running, and to Robyn Maina for taking over in 2019.

 

International Journal Watch

SPANZA Journal Watch was recognised as a great initiative, and APAGBI thought that it would be a great thing for them to adopt.  SPANZA is now working with APAGBI to create the ‘International Journal Watch’.

CLICK HERE to go to the APAGBI Journal Watch site.

Journal Watch Search

211 Results Found

Pediatric lower limb peripheral nerve blocks: Indications, effectiveness, and the incidence of adverse events.

What?

A review of 1438 lower limb nerve blocks in 1038 children.

Where?

Royal Children’s Hospital, Melbourne

How?

Retrospective review of prospective data from 2016-2021 in children who had had lower limb surgery. Data obtained from the electronic record included demographics, type of block, technique, catheter use, adjuvant drugs used.

Findings

There were a wide range of surgical indications.

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Clonidine Versus Midazolam Premedication and Postoperative Negative Behavioral Changes in Younger Children: A Randomized Controlled Trial.

Children are known to potentially suffer negative behavioural changes (NBC) following general anaesthesia and surgical/diagnostic procedures. These may be new or a worsening of pre-existing behaviour. Premedications such as midazolam and clonidine are thought to not only help allay preoperative anxiety, but possibly reduce the incidence of NBCs. Clonidine’s longer lasting sedative effect may make it better at limiting postoperative NBCs.

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Patient and operative factors associated with unanticipated intensive care admission and outcomes following posterior fossa decompressions in children: A retrospective study.

Summary

  • This retrospective chart review examined the medical records of all patients under 18 years who underwent surgery for Chiari I malformation between 2009 and 2021 at a single specialist centre in Chicago.
  • The primary outcome was the incidence of unanticipated admission to ICU with the primary variable of interest being anaesthesia-related complications.
  • 296 patients were identified. 25 patients (8.4%) had 29 anaesthesia-related intraoperative complications.
  • 5 patients (0.7%) had unanticipated ICU admission
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Dexmedetomidine as a sole sedative for procedural sedation in preterm and neonate infants: A retrospective analysis.

Study summary

This is a retrospective single-center cohort study from University Hospital of Cologne, Germany looking at use of IV dexmedetomidine as sedation for MRI in premature and term infants less than 60 weeks post-conceptual age weighing <5kg. Exclusion criteria were ASA-5 patients, and those already intubated.

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Straight-tip guidewire versus J-tip guidewire for central venous catheterisation in neonates and small infants: A randomised controlled trial. Population Pharmacokinetics of Intranasal Dexmedetomidine in Infants and Young Children.

Study summary

This is a single-centre prospective study looking at the pharmacokinetic profile of 2 mcg/kg intranasal (IN) dexmedetomidine administered to 137 ASA 1-2 Chinese children aged 3-36 months, with simple vascular malformations undergoing interventional radiological procedures between June 2016 to November 2017 at Guangzhou Women and Children’s Medical Center, China. Exclusion criteria were dexmedetomidine allergy or hypersensitivity; severe hepatic impairment; haematological, cardiovascular, endocrine, metabolic, and gastrointestinal diseases; any sedative exposure including dexmedetomidine within a week; presence of active respiratory symptoms, rhinorrhoea and vascular malformations in or near the nasal cavity that might influence nasal drug absorption.

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Risk factors for administration of additional reversal following neuromuscular blockade with rocuronium in children: A retrospective case-control study.

Summary

This is a retrospective case control study of electronic records in <18-year-olds from one institution between 2017-2020. Of 6373 patients who received neostigmine after rocuronium paralysis, 101 patients received a second dose of reversal (1.58%), 36 with sugammadex and 65 with an additional neostigmine dose.

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Complications associated with paediatric airway management during the COVID-19 pandemic: an international, multicentre, observational study [published online ahead of print, 2022 Mar 23].

This multicentre observational study was designed to bridge the gap in knowledge about potential adverse respiratory events during airway management in children with COVID-19 with a lot of earlier data reliant on adult studies.

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