Hypoxemia in Young Children Undergoing One-lung Ventilation: A Retrospective Cohort Study.

One lung ventilation in children remains a specialised practice in children performed by either endobronchial intubation or use of a bronchial blocker. With low case numbers, assessment of best practice is difficult. This retrospective cohort study interrogated data from a large multicentre cohort of children (aged 2 months to 3 years) undergoing one-lung ventilation for […]

Risk factors for anesthetic-related complications in pediatric patients with a newly diagnosed mediastinal mass.

Study design   Single centre, retrospective case review. Aim Identification of risk factors for anaesthetic-related complications in paediatric patients with any type of mediastinal mass. Methods CT scans of patients presenting to Children’s Mercy Hospital, Kansas City between 2008-2019 were queried for “mediastinal mass”. Cardiac and respiratory symptoms were recorded and a blinded radiologist reviewed the […]

Neonatal resuscitation: current evidence and guidelines

This article serves as a review of neonatal resuscitation guidelines which may be of interest to the obstetric anaesthetist involved in the care of newborns at the time of birth. Cord management: Deferred clamping for 1-2 minutes allows an increased blood volume to be transferred from the placenta to the newborn, with evidence for lower […]

Population pharmacokinetics of oxycodone: Premature neonates to adults.

This is a pooled data study to describe oxycodone pharmacokinetics in premature neonates to adults, when administered via intravenous, nasogastric, buccal and epidural routes. The study also assessed the impact of body composition on oxycodone pharmacokinetics. Methods: Pooled data from four studies to assess oxycodone pharmacokinetics following surgical procedures. Plasma concentration data were collected following […]

Postoperative Hematocrit and Adverse Outcomes in Pediatric Cardiac Surgery Patients: A Cross-Sectional Study From the Society of Thoracic Surgeons and Congenital Cardiac Anesthesia Society Database Collaboration.

Study type: A retrospective cross-sectional study Methods: The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS-CHSD) and Congenital Cardiac Anesthesia Society Database Module (2014-2019) were accessed. These are databases of congenital and paediatric cardiac surgical operations in North America. Multivariable logistic regression models, adjusting for covariates in the STS-CHSD mortality risk model, were used […]

. Impact of Modified Anesthesia Management for Pediatric Patients With Williams Syndrome.

Background This retrospective observational cohort study at a single quaternary paediatric surgical centre aimed to assess the impact of a risk-based care protocol for children with Williams Syndrome (WS) undergoing general anaesthesia. Williams syndrome is a congenital multisystem disorder involving connective tissue, cardiovascular and the central nervous system. It effects approximately 1 in 10,000 live […]

Anesthesiologist-related factors associated with risk-adjusted pediatric anesthesia-related cardiopulmonary arrest: a retrospective two level analysis.

Introduction This single-centre, retrospective study examines the impact of anesthesiologist-related factors on anesthesia-related cardiac arrest and is an attempt to replicate the results of the work by Zgleszewski et al, in 2016. The latter showed a higher risk of anesthesia-related cardiac arrest for anesthesiologists with lower annual days of delivering anesthetics. Methods The 10-year data […]